Article
Generation of hydrogen peroxide from mutant forms of the prion protein fragment PrP121-231.
Biochemistry - 1 Jul 2003
Turnbull Stuart, Tabner Brian J, Brown David R, Allsop David
Abstract excerpt
By means of electron spin resonance spectroscopy, in conjunction with the spin trapping technique, we have shown previously that Abeta and alpha-synuclein (aggregating proteins that accumulate in the brain in Alzheimer's disease, Parkinson's disease, and related disorders) both induce the formati...
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