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Article

Time-dependent amplified pharmacokinetic and pharmacodynamic responses of rabeprazole in cytochrome P450 2C19 poor metabolizers.

Pharmacotherapy - 1 Jun 2003

Lin Chun-Jung, Yang Jyh-Chin, Uang Yow-Shieng, Chern Herng-Der, Wang Teh-Hong

Abstract excerpt

STUDY OBJECTIVES: To determine the pharmacokinetic and pharmacodynamic rationale for the optimum regimen of rabeprazole in the treatment of Helicobacter pylori infection in patients who are cytochrome P450 (CYP) 2C19 poor metabolizers or extensive metabolizers. DESIGN: Prospective, multiple-dose pharmacokinetic and pharmacodynamic study. SETTING: University-affiliated medical center in Taiwan. SUBJECTS: Twelve...

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PMID: 12820812
DOI: 10.1592/phco.23.6.711.32177

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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