Article
Efficacy of triple therapy with rabeprazole for Helicobacter pylori infection in relation to CYP2C19 genotype.
The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi - 1 Dec 2003
Lee Sang Bae, Park Sang Jong, Ryu Ji Kon, Lee Jin Kwang, Kim Hoi Jin, Bae Jin Soo, Jung Hyun Seung, Park Sil Moo
Abstract excerpt
BACKGROUND/AIMS: Genetic polymorphism of cytochrome P450 CYP2C19 influences the efficacy of proton pump inhibitor (PPI) in Helicobacter pylori (H. pylori) eradication therapy. We investigated the difference in the cure rates of H. pylori infection by triple (rabeprazole plus amoxacillin and clarithromycin) therapy in relation to CYP2C19 genotype status. METHODS: One hundred and sixteen H. pylori infected patients...
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