Article
Effect of CYP2C19 genotypes on the pharmacokinetic/pharmacodynamic relationship of rabeprazole after a single oral dose in healthy Chinese volunteers.
European journal of clinical pharmacology - 1 Nov 2010
Sheng Yu-Cheng, Wang Kun, He Ying-Chun, Yang Juan, Zheng Qing-Shan
Abstract excerpt
AIMS: To explore the pharmacokinetic/pharmacodynamic relationship of rabeprazole and the role of CYP2C19 genotypes after a single oral dose in healthy Chinese volunteers by a population approach. METHODS: Plasma concentration time profile data and intragastric pH values of 19 genotyped healthy male adults after a single oral dose of rabeprazole in an open label randomized fashion were used for this population...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
