Article
Pharmacodynamic effects and kinetic disposition of rabeprazole in relation to CYP2C19 genotype in healthy Chinese subjects.
Acta pharmacologica Sinica - 1 Mar 2005
Hu Yong-mei, Xu Jian-ming, Mei Qiao, Xu Xin-hua, Xu Shu-yun
Abstract excerpt
AIM: To investigate whether the pharmacodynamics and pharmacokinetics of rabeprazole are dependent on CYP2C19 genotype status in healthy Chinese Han subjects. METHODS: The CYP2C19 genotype status of healthy Chinese Han volunteers was determined using the polymerase chain reaction-restriction frag...
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