Article
The Delta subunit of RNA polymerase is required for virulence of Streptococcus agalactiae.
Infection and immunity - 1 Jul 2003
Jones Amanda L, Needham Rachel H V, Rubens Craig E
Abstract excerpt
Group B streptococci (GBS) remain the most significant bacterial pathogen causing neonatal sepsis, pneumonia, and meningitis in the United States despite the chemoprophylaxis strategies for preventing infection recommended by the Centers for Disease Control and Prevention. Using signature-tagged transposon mutagenesis to screen for novel virulence factors, we identified the rpoE gene as essential for development...
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