Article
Identification of conditionally essential genes for Streptococcus suis infection in pigs.
Virulence - 1 Dec 2020
Arenas Jesús, Zomer Aldert, Harders-Westerveen Jose, Bootsma Hester J, De Jonge Marien I, Stockhofe-Zurwieden Norbert, Smith Hilde E, De Greeff Astrid
Abstract excerpt
Streptococcus suis is a Gram-positive bacterium and zoonotic pathogen that causes meningitis and sepsis in pigs and humans. The aim of this study was to identify genes required for S. suis infection. We created Tn-Seq libraries in a virulent S. suis strain 10, which was used to inoculate pigs in an intrathecal experimental infection. Comparative analysis of the relative abundance of mutants recovered from...
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