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Article

Epigenetic alterations of the keratin 13 gene in oral squamous cell carcinoma

1 Dec 2014

Abstract excerpt

BACKGROUND: Epigenetic modifications play important roles in the regulation of gene expression determining cellular phenotype as well as various pathologies such as cancer. Although the loss of keratin 13 (KRT13) is reportedly linked to malignant transformation of oral epithelial cells, the molecular mechanisms through which KRT13 is repressed in oral squamous cell carcinoma (OSCC) remain unclear. The aim of this...

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PMID: 25527207
DOI: 10.1186/1471-2407-14-988

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