Article
The dynamics of the genotype-phenotype association.
Poultry science - 1 Jun 2003
Kuhnlein U, Parsanejad R, Zadworny D, Aggrey S E
Abstract excerpt
The integrity of an organism is maintained by networks of interacting genes. Such networks predict that genetic variants affect phenotypes in a nonadditive fashion. That is, the effect of an allelic variation in one gene is dependent on the variations in other genes. We summarize the analyses of a series of genes in a White Leghorn strain that support the existence of such gene networks: 1) genes are pleiotropic,...
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