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Article

Non-MHC-linked genes in autoimmune diseases.

Current opinion in immunology - 1 Dec 1992

Garchon H J

Abstract excerpt

The gene responsible for the lpr mutation in MRL mice that are prone to systemic lupus erythematosus has been shown to encode the apoptosis-inducing Fas antigen, thus pointing to control of apoptosis as a major regulatory mechanism in autoimmunity. In the non-obese diabetic mouse model for insuli...

Topics

Animals
Antigens, Surface
Autoimmune Diseases
Chromosome Mapping
Diabetes Mellitus, Type 1
Genes, Immunoglobulin
Genetic Predisposition to Disease
Humans
Mice
Mice, Inbred NOD
Mice, Mutant Strains
Receptors, Antigen, T-Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

fas Receptor

Source

Identifiers

PMID: 1281639
DOI: 10.1016/0952-7915(92)90051-f

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1281639-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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