Article
[Neuropathological findings in early-onset Alzheimer's disease (E280a-PS1 mutation)].
Revista de neurologia - 1 Jan 2000
Duque-Castaño A, Roldán M I, Arango-Viana J C, Arcos-Burgos M, Cubillo H, Lopera F
Abstract excerpt
INTRODUCTION AND MATERIAL: Nine brains belonging to early onset Alzheimer disease (E280A-PS1 mutation) affected individuals from Antioquia, Colombia, were analyzed by neuropathological standard techniques. All individuals were ascertained from genealogies descendents from a common ancestor that shows a dominant autosomical pattern of inheritance. RESULTS: All cases analyzed were carriers to the E280A-PS1...
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