Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Vitamin D receptor start codon polymorphism and colorectal cancer risk: effect modification by dietary calcium and fat in Singapore Chinese.

Carcinogenesis - 1 Jun 2003

Wong Hui-Lee, Seow Adeline, Arakawa Kazuko, Lee Hin-Peng, Yu Mimi C, Ingles Sue A

Abstract excerpt

Vitamin D has been implicated as a protective agent against colorectal cancer. We hypothesized that a functional start codon polymorphism in the vitamin D receptor (VDR) influences the risk of colorectal carcinoma. We conducted a case-control study nested within a large cohort of Singapore Chinese. VDR genotypes, determined by FokI restriction endonuclease digestion of PCR-amplified DNA, were performed on 217...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcium, Dietary
Share to China

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Codon, Initiator

Share to Colorectal Neoplasms

Share to Dietary Fats

Share to Receptors, Calcitriol

Share to Singapore

Source

Identifiers

PMID: 12807755
DOI: 10.1093/carcin/bgg059

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Vitamin D receptor start codon polymorphism and colorectal cancer risk: effect modification by dietary calcium and fat in Singapore Chinese.PMID 12807755Read ↗

Modification of the inverse association between dietary vitamin D intake and colorectal cancer risk by a FokI variant supports a chemoprotective action of Vitamin D intake mediated through VDR binding.Semantic proximity Read ↗

Start codon polymorphisms in the vitamin D receptor and colorectal cancer risk.Semantic proximity Read ↗

Vitamin D receptor FokI polymorphism and the risks of colorectal cancer, inflammatory bowel disease, and colorectal adenoma.Semantic proximity Read ↗

Dietary calcium, vitamin D, VDR genotypes and colorectal cancer.Semantic proximity Read ↗

Vitamin D receptor polymorphisms in colorectal cancer in New Zealand: an association study.Semantic proximity Read ↗

Investigation of the VDR gene polymorphisms association with susceptibility to colorectal cancer.Semantic proximity Read ↗

Calcium, vitamin D, VDR genotypes, and epigenetic and genetic changes in rectal tumors.Semantic proximity Read ↗

Vitamin D receptor gene polymorphisms and the risk of colorectal cancer in a Chinese population.Semantic proximity Read ↗

Vitamin D receptor FokI gene polymorphisms may be associated with colorectal cancer among African American and Hispanic participants.Semantic proximity Read ↗

Associations between vitamin D receptor (VDR) gene polymorphisms and colorectal cancer risk and effect modifications of dietary calcium and vitamin D in a Japanese population.Semantic proximity Read ↗

The -4817 G>A (rs2238136) variant of the vitamin D receptor gene: a probable risk factor for colorectal cancer.Semantic proximity Read ↗

The vitamin D receptor gene start codon polymorphism: a functional analysis of FokI variants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.