Article
Vitamin D receptor FokI gene polymorphisms may be associated with colorectal cancer among African American and Hispanic participants.
Cancer - 1 May 2014
Sarkissyan Marianna, Wu Yanyuan, Chen Zujian, Mishra Dhruva K, Sarkissyan Suren, Giannikopoulos Ioannis, Vadgama Jaydutt V
Abstract excerpt
BACKGROUND: Vitamin D plays a role in cancer tumorogenesis and acts through the vitamin D receptor (VDR). Although African Americans have the lowest serum vitamin D levels, supplementation has not yielded a significant improvement in cancer. Gene polymorphisms in VDR may play a role. There is a dearth of information on VDR gene polymorphisms and colorectal cancer (CRC) among under-represented ethnic groups. In...
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