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Article

Essential 110Cys in active site of membrane-associated prostaglandin E synthase-2.

Biochemical and biophysical research communications - 27 Jun 2003

Watanabe Kikuko, Ohkubo Hiroaki, Niwa Haruki, Tanikawa Naomi, Koda Noriko, Ito Seiji, Ohmiya Yoshihiro

Abstract excerpt

The amino acid sequence of membrane-associated prostaglandin (PG) E synthase-2 (mPGE synthase-2), which has a broad specificity in its thiol requirement for a catalytic activity, has the consensus region from 104Leu to 120Leu found in glutaredoxin and of thioredoxin. The sequence of Cys-x-x-Cys i...

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PMID: 12804604
DOI: 10.1016/s0006-291x(03)01025-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12804604-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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