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Article

Telomeres and Telomerase in Aging, Regeneration and Cancer

1 Apr 2003

Abstract excerpt

The finding that telomere shortening limits the replicative lifespan of primary human cells has fueled speculations that telomere shortening plays a role during aging and regeneration of tissues in vivo. Support for this hypothesis comes from studies showing telomere shortening in a variety of human tissues as a consequence of aging and chronic disease. Studies in telomerase-deficient mice have given first...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 12803478
DOI: 10.1016/s1016-8478(23)13723-x

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