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Article

Flt-3 and c-kit mutation studies in a spectrum of chronic myeloid disorders including systemic mast cell disease.

Leukemia research - 1 Aug 2003

Pardanani Animesh, Reeder Terra L, Kimlinger Teresa K, Baek Jin Y, Li Chin-Y, Butterfield Joseph H, Tefferi Ayalew

Abstract excerpt

We screened 115 patients with chronic myeloid disorders (CMD) for known flt-3 and c-kit mutations in both the juxtamembrane (JM) and the activation loop (AL) domains. None of the patients displayed flt-3 (JM or AL) or c-kit JM mutations. However, the c-kit AL (D816V) mutation was detected in 5 of...

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Source

Identifiers

PMID: 12801532
DOI: 10.1016/s0145-2126(02)00303-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12801532-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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