Article
Variable presence of KITD816V in clonal haematological non-mast cell lineage diseases associated with systemic mastocytosis (SM-AHNMD).
The Journal of pathology - 1 Apr 2010
Sotlar Karl, Colak Sema, Bache Anja, Berezowska Sabina, Krokowski Manuela, Bültmann Burkhard, Valent Peter, Horny Hans-Peter
Abstract excerpt
In a substantial number of patients with systemic mastocytosis (SM), an associated clonal haematological non-mast cell lineage disease (AHNMD) is detectable. Although most of these patients display KIT mutations, especially KIT(D816V), little is known about their exact frequency and their distribution in AHNMD subtypes. We examined 48 patients with SM-AHNMD for the presence of mutant KIT in the SM and AHNMD...
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