Article
Quaking phenotype influences brain lipid-related mRNA levels.
Neuroscience letters - 20 Jul 1992
DeWille J W, Farmer S J
Abstract excerpt
Although lipids compose almost 80% of myelin, the influence of quaking on mRNAs encoding lipid biosynthetic enzymes and transport proteins has not been previously reported. Understanding the influence of quaking on myelin-specific and lipid-related mRNAs will be useful in determining the mechanism of the quaking defect. Stearoyl CoA desaturase (SCD) catalyzes a key step in the biosynthesis of oleic acid (C18:1,...
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