Article
Alpha-synuclein: between synaptic function and dysfunction.
Histology and histopathology - 1 Oct 2003
Di Rosa G, Puzzo D, Sant'Angelo A, Trinchese F, Arancio O
Abstract excerpt
Alpha-synuclein belongs to a family of vertebrate proteins, encoded by three different genes: alpha, ss, and gamma. The protein has become of interest to the neuroscience community in the last few years after the discovery that a mutation in the alpha-synuclein gene is associated with familial autosomal-dominant early-onset forms of Parkinson Disease. However, it is not yet clear how the protein is involved in...
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