Article
Mutation frequency of plasmid DNA and Escherichia coli following long-term space flight on Mir.
Journal of radiation research - 1 Dec 2002
Takahashi Akihisa, Ohnishi Ken, Yokota Akitoshi, Kumagai Tsukasa, Nakano Tamotsu, Ohnishi Takeo
Abstract excerpt
To elucidate the biological influence of space radiation, we studied the effects of long-term space flight on mutation of the bacterial ribosomal protein L gene (rpsL). We prepared dried samples of plasmid DNA and repair-deficient and wild type cells of Escherichia (E.) coli. After a 40-day space flight on board the Russian space station Mir, the mutation frequencies of the rpsL gene were estimated by...
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