Article
Clinico-biologic features and treatment outcome of adult pro-B-ALL patients enrolled in the GIMEMA 0496 study: absence of the ALL1/AF4 and of the BCR/ABL fusion genes correlates with a significantly better clinical outcome.
Blood - 15 Sept 2003
Cimino Giuseppe, Elia Loredana, Mancini Marco, Annino Luciana, Anaclerico Barbara, Fazi Paola, Vitale Antonella, Specchia Giorgina, Di Raimondo Francesco, Recchia Anna, Cuneo Antonio, Mecucci Cristina, Pane Fabrizio, Saglio Giuseppe, Foa Robin, Mandelli Franco
Abstract excerpt
To elucidate the biologic and clinical heterogeneity of adult pro-B acute lymphoblastic leukemia (ALL) (ie, terminal deoxynucletidyl-transferase-positive[TdT+], CD19+, CD10-, surface immunoglobulin-negative [SIg-]), we evaluated 66 patients enrolled in the Italian multicentric Gruppo Italiano Malattie Ematologiche dell'Adulto (GIMEMA) 0496 study between October 1996 and December 1999. The ALL1/AF4 fusion...
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