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Memory B cells producing somatically mutated antiphospholipid antibodies are present in healthy individuals

5 Jun 2003

Abstract excerpt

Antiphospholipid antibodies (aPLs) are associated with thrombosis and recurrent abortions during autoimmune pathologies, but they are also produced in healthy individuals and during infectious diseases. To analyze the possible links between physiologic and pathologic aPLs, it is of importance to characterize normal aPL production. We took advantage of the known tropism of Epstein-Barr virus (EBV) for B cells in...

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PMID: 12791657
DOI: 10.1182/blood-2003-01-0180

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