Article
The role of TIGR and OPTN in Finnish glaucoma families: a clinical and molecular genetic study.
Molecular vision - 30 May 2003
Forsman Eva, Lemmelä Susanna, Varilo Teppo, Kristo Paula, Forsius Henrik, Sankila Eeva-Marja, Järvelä Irma
Abstract excerpt
PURPOSE: The aim of the present study was to analyze the role of the two primary open angle glaucoma (POAG) genes, trabecular meshwork-induced glucocorticoid response (TIGR/MYOC) and optineurin (OPTN), in Finnish glaucoma families originating from southern coast of Finland. METHODS: In total, 136 patients were examined to determine their ophthalmological status. Genealogical studies were performed using church...
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