[Study on MYOC/TIGR gene mutations in primary open-angle glaucoma].

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Article

[Study on MYOC/TIGR gene mutations in primary open-angle glaucoma].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology - 1 Feb 2011

Chen Jian-Hua, Xu Liang, Li Yang, Dong Bing

Abstract excerpt

OBJECTIVE: To study the mutations in the trabecular meshwork induced-glucocorticoid response protein gene (TIGR/MYOC) in Chinese POAG patients. METHODS: It was a case-control study. One hundred and eighteen Chinese patients with POAG and 150 control subjects without POAG were screened for coding sequence of the MYOC gene by polymerase chain reaction, single-strand conformation polymorphism (SSCP) and DNA...

Topics

Adolescent
Adult
Aged
Case-Control Studies
Child
Cytoskeletal Proteins
DNA Mutational Analysis
Eye Proteins
Female
Glaucoma, Open-Angle
Glycoproteins
Humans
Middle Aged
Mutation
Young Adult

Source

Open in PubMed

Identifiers

PMID: 21426841

Genes

MYOC

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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