Article
Microbial isoprenoid biosynthesis and human gammadelta T cell activation.
FEBS letters - 5 Jun 2003
Eberl Matthias, Hintz Martin, Reichenberg Armin, Kollas Ann-Kristin, Wiesner Jochen, Jomaa Hassan
Abstract excerpt
Human Vgamma9/Vdelta2 T cells play a crucial role in the immune response to microbial pathogens, yet their unconventional reactivity towards non-peptide antigens has been enigmatic until recently. The break-through in identification of the specific activator was only possible due to recent success in a seemingly remote field: the elucidation of the reaction steps of the newly discovered...
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