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Article

Isoprenoid biosynthesis in hereditary periodic fever syndromes and inflammation.

Cellular and molecular life sciences : CMLS - 1 Jun 2003

Houten S M, Frenkel J, Waterham H R

Abstract excerpt

Mevalonate kinase (MK) is an essential enzyme in the isoprenoid biosynthesis pathway which produces numerous biomolecules (isoprenoids) involved in a variety of cellular processes. The indispensability of MK and isoprenoid biosynthesis for human health is demonstrated by the identification of its deficiency as the biochemical and molecular cause of the inherited autoinflammatory disorders mevalonic aciduria and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12861380
DOI: 10.1007/s00018-003-2296-4
PMCID: PMC11146049

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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