Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HMGA2 is expressed in an allele-specific manner in human lipomas.

Cancer genetics and cytogenetics - 1 Jun 2003

Ashar Hena R, Tkachenko Alexei, Shah Pritesh, Chada Kiran

Abstract excerpt

The architectural transcription factor HMGA2 is almost exclusively expressed in undifferentiated mesenchymal cells. Interestingly, it has been mapped to the translocation site in a variety of human mesenchymal tumors that reveal a terminally differentiated phenotype. The expression of chimeric HMGA2 transcripts encoding three DNA-binding domains fused to novel transcriptional regulatory domains was previously...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 5' Untranslated Regions
Share to Amino Acid Sequence
Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HMGA2 Protein

Share to Lipoma

Share to Microsatellite Repeats

Share to Reverse Transcriptase Polymerase Chain Reaction

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 12781451
DOI: 10.1016/s0165-4608(03)00037-2

Genes

HMGA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HMGA2 is expressed in an allele-specific manner in human lipomas.PMID 12781451Read ↗

Expression levels of HMGA2 in adipocytic tumors correlate with morphologic and cytogenetic subgroupsSemantic proximity Read ↗

Misexpression of disrupted HMGI architectural factors activates alternative pathways of tumorigenesis.Semantic proximity Read ↗

Misexpression of Full-length HMGA2 Induces Benign Mesenchymal Tumors in MiceSemantic proximity Read ↗

Role of the high mobility group A proteins in human lipomasSemantic proximity Read ↗

Translocation (Y;12) in lipoma.Semantic proximity Read ↗

Assessment of the clinical and molecular impact of different cytogenetic subgroups in a series of 272 lipomas with abnormal karyotypeSemantic proximity Read ↗

Recent Advancement in Atypical Lipomatous Tumor Research.Semantic proximity Read ↗

Liposarcoma: Advances in Cellular and Molecular Genetics Alterations and Corresponding Clinical TreatmentSemantic proximity Read ↗

Chromosomal Translocations in Benign Tumors:<i>The HMGI Proteins</i>Semantic proximity Read ↗

A novel HMGA2::KITLG fusion in a dedifferentiated liposarcoma with amplification of MDM2 and HMGA2Semantic proximity Read ↗

Constitutional rearrangement of the architectural factor HMGA2: a novel human phenotype including overgrowth and lipomas.Semantic proximity Read ↗

Translocation breakpoints upstream of theHMGIC gene in uterine leiomyomata suggest dysregulation of this gene by a mechanism different from that in lipomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.