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Article

Purifying mRNAs with a high-affinity eIF4E mutant identifies the short 3' poly(A) end phenotype.

Proceedings of the National Academy of Sciences of the United States of America - 10 Jun 2003

Choi Youkyung Hwang, Hagedorn Curt H

Abstract excerpt

The use of DNA microarrays has revolutionized the manner in which mRNA populations are analyzed. One limitation of the current technology is that mRNAs are often purified on the basis of their 3' poly(A) ends, which can be extremely short or absent in some mRNAs. To circumvent this limitation, we have developed a procedure for the purification of eukaryotic mRNAs using a mutant version of the mRNA 5' cap-binding...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Oligodeoxyribonucleotides

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Source

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Identifiers

PMID: 12777618
DOI: 10.1073/pnas.1232347100
PMCID: PMC165825

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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