Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cyclin D1 overexpression in bronchial epithelia of patients with lung cancer is associated with smoking and predicts survival.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Jun 2003

Ratschiller D, Heighway J, Gugger M, Kappeler A, Pirnia F, Schmid R A, Borner M M, Betticher D C

Abstract excerpt

PURPOSE: Cyclin D1 is overexpressed in almost 60% of resectable non-small-cell lung cancer (NSCLC). In the absence of cyclin D1 gene amplification, overexpression is characterized by allelic imbalanced transcript levels. METHODS: The aims were to study cyclin D1 expression by immunohistochemistry and allelic balance of transcripts in tumor-free bronchial epithelia from patients with resectable NSCLC by using...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Non-Small-Cell Lung
Share to Cyclin D1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Proportional Hazards Models

Share to Respiratory Mucosa

Share to Smoking

Share to Statistics, Nonparametric

Share to Survival Rate

Share to Switzerland

Source

Identifiers

PMID: 12775733
DOI: 10.1200/JCO.2003.03.103

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cyclin D1 overexpression in bronchial epithelia of patients with lung cancer is associated with smoking and predicts survival.PMID 12775733Read ↗

Molecular and immunohistochemical analysis of thebcl-1/cyclin D1 gene in laryngeal squamous cell carcinomasSemantic proximity Read ↗

In-depth analysis of molecular alterations within normal and tumour tissue from an entire bronchial tree.Semantic proximity Read ↗

Prognostic significance of CCND1 (cyclin D1) overexpression in primary resected non-small-cell lung cancer.Semantic proximity Read ↗

Cyclin D1 protein expression and function in human breast cancerSemantic proximity Read ↗

Cyclin D1 (CCND1) A870G gene polymorphism modulates smoking-induced lung cancer risk and response to platinum-based chemotherapy in non-small cell lung cancer (NSCLC) patients.Semantic proximity Read ↗

Association of p16 homozygous deletions with clinicopathologic characteristics and EGFR/KRAS/p53 mutations in lung adenocarcinoma.Semantic proximity Read ↗

Molecular Characteristics of ERCC1-Negative versus ERCC1-Positive Tumors in Resected NSCLC.Semantic proximity Read ↗

Clinical significance of PD-L1 and PD-L2 copy number gains in non-small-cell lung cancer.Semantic proximity Read ↗

Association between CCND1 G/A870 polymorphism, allele-specific amplification, cyclin D1 expression, and survival in esophageal and lung carcinoma.Semantic proximity Read ↗

G1 control gene status is frequently altered in resectable non-small cell lung cancer.Semantic proximity Read ↗

Loss of BRCA1-associated protein 1 ( BAP1 ) expression is rare in non–small cell lung cancerSemantic proximity Read ↗

Bronchial malondialdehyde DNA adducts, tobacco smoking, and lung cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.