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Article

CD105 is important for angiogenesis: evidence and potential applications.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jun 2003

Duff Sarah E, Li Chenggang, Garland John M, Kumar Shant

Abstract excerpt

Angiogenesis is the propelling force for tumor growth and metastasis, and antiangiogenic therapy represents one of the most promising modalities for cancer treatment. CD105 (endoglin) is a proliferation-associated and hypoxia-inducible protein abundantly expressed in angiogenic endothelial cells (EC). It is a receptor for transforming growth factor (TGF) -beta1 and -beta3 and modulates TGF-beta signaling by...

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Source

Identifiers

PMID: 12773481
DOI: 10.1096/fj.02-0634rev

Genes

MVD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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