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Article

Halophilic adaptation of protein-DNA interactions.

Biochemical Society transactions - 1 Jun 2003

Bergqvist S, Williams M A, O'Brien R, Ladbury J E

Abstract excerpt

Pyrococcus woesei ( Pw ) is an archaeal organism adapted to living in conditions of elevated salt and temperature. Thermodynamic data reveal that the interaction between the TATA-box-binding protein (TBP) from this organism and DNA has an entirely different character to the same interaction in mesophilic counterparts. In the case of the Pw TBP, the affinity of its interaction with DNA increases with increasing...

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Identifiers

PMID: 12773181
DOI: 10.1042/bst0310677

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TBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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