Article
Differential UVC-induced gadd45 gene expression in xeroderma pigmentosum cells.
Biochemical and biophysical research communications - 13 Jun 2003
Chang Hsien-Chang, Tsai Ju- He, Guo Yueliang Leon, Huang Yu-Hsin, Tsai Han-Ni, Tsai Pei-Chien, Huang Wenya
Abstract excerpt
Xeroderma pigmentosum C (XPC) is a DNA repair factor essential for global genome repair (GGR) in nucleotide excision repair (NER). In the present study we screened for factors regulated by XPC after DNA damage. Ultraviolet C (UVC) irradiation-induced stress response factors were analyzed by a cDNA microarray chip system in HeLa and XP4PA-SV xpc mutant cell lines. The principal component analysis (PCA) method was...
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