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HER 2/neu expression and gene amplification in colon cancer

15 May 2003

Abstract excerpt

HER 2/neu is an important oncogene in breast cancer, but the prevalence and significance of HER 2/neu gene amplification in colon cancer have been poorly documented. We have evaluated HER 2/neu gene amplification and protein overexpression in a series of colon cancers to assess the frequency, concordance and clinical significance of these events. HER 2/neu gene copy number was measured in 154 primary colon...

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PMID: 12767065
DOI: 10.1002/ijc.11137

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