Article
The HER-2/neu oncogene in tumors of the gastrointestinal tract.
Cancer investigation - 1 Jan 2001
Ross J S, McKenna B J
Abstract excerpt
The HER-2/neu oncogene is localized to chromosome 17q and shares significant homology with the epidermal growth factor receptor. As a result of its potential role in the selection of therapy, HER-2/neu testing has reached near-standard-of-practice status in breast cancer. There is considerable interest in HER-2/neu as a prognostic factor and target of therapy in tumors of the gastrointestinal tract. In this...
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