Article
Involvement of ClpX protein in the post-transcriptional regulation of a competence specific transcription factor, ComK protein, of Bacillus subtilis.
Journal of biochemistry - 1 Mar 2003
Nanamiya Hideaki, Shiomi Emiko, Ogura Mitsuo, Tanaka Teruo, Asai Kei, Kawamura Fujio
Abstract excerpt
ComK protein of Bacillus subtilis positively regulates the transcription of several late competence genes as well as comK itself. We constructed a clpX disrupted mutant of B. subtilis and studied its effect on the regulation of ComK activation. When Pspac, which controls the comK gene in a multicopy plasmid, was induced by the addition of IPTG, comK transcripts were detected in both the clpX mutant and the wild...
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