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Article

HnRNP G and Tra2beta: opposite effects on splicing matched by antagonism in RNA binding

21 May 2003

Abstract excerpt

The hnRNP G family comprises three closely related proteins, hnRNP G, RBMY and hnRNP G-T. We showed previously that they interact with splicing activator proteins, particularly hTra2beta, and suggested that they were involved in regulating Tra2-dependent splicing. We show here that hnRNP G and hTra2beta have opposite effects upon the incorporation of several exons, both being able to act as either an activator or...

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PMID: 12761049
DOI: 10.1093/hmg/ddg136

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