Article
Gene expression phenotypic models that predict the activity of oncogenic pathways.
Nature genetics - 1 Jun 2003
Huang Erich, Ishida Seiichi, Pittman Jennifer, Dressman Holly, Bild Andrea, Kloos Mark, D'Amico Mark, Pestell Richard G, West Mike, Nevins Joseph R
Abstract excerpt
High-density DNA microarrays measure expression of large numbers of genes in one assay. The ability to find underlying structure in complex gene expression data sets and rigorously test association of that structure with biological conditions is essential to developing multi-faceted views of the gene activity that defines cellular phenotype. We sought to connect features of gene expression data with biological...
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