Article
Association between interleukin 6 promoter variants and chronic hepatitis B progression.
Experimental & molecular medicine - 30 Apr 2003
Park Byung Lae, Lee Hyo-Suk, Kim Yoon Jun, Kim Jun Yeon, Jung Ji Hyun, Kim Lyoung Hyo, Shin Hyoung Doo
Abstract excerpt
Interleukin 6 (IL6) plays an essential role in the regulation of immune response to chronic disease. In this study, the three known single nucleotide polymorphisms (SNPs) in the IL6 promoter region were genotyped in a large chronic hepatitis B cohort to evaluate the effects of IL6 promoter variants. The single base extension method was used for this genotyping. Haplotypes were constructed by the three SNPs in...
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