Article
Screening of human primary melanocytes of defined melanocortin-1 receptor genotype: pigmentation marker, ultrastructural and UV-survival studies.
Pigment cell research - 1 Jun 2003
Leonard J Helen, Marks Lisa H, Chen Wei, Cook Anthony L, Boyle Glen M, Smit Darren J, Brown Darren L, Stow Jennifer L, Parsons Peter G, Sturm Richard A
Abstract excerpt
Recent population studies have demonstrated an association with the red-hair and fair-skin phenotype with variant alleles of the melanocortin-1 receptor (MC1R) which result in amino acid substitutions within the coding region leading to an altered receptor activity. In particular, Arg151Cys, Arg160Trp and Asp294His were the most commonly associated variants seen in the south-east Queensland population with at...
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