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Article

NFATc3 and NFATc4 are required for cardiac development and mitochondrial function.

Circulation research - 27 Jun 2003

Bushdid Paul B, Osinska Hanna, Waclaw Ronald R, Molkentin Jeffery D, Yutzey Katherine E

Abstract excerpt

Activation of the nuclear factor of activated T-cell (NFAT) family of transcription factors is associated with changes in gene expression and myocyte function in adult cardiac and skeletal muscle. However, the role of NFATs in normal embryonic heart development is not well characterized. In this report, the function of NFATc3 and NFATc4 in embryonic heart development was examined in mice with targeted disruption...

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Share to Bromodeoxyuridine
Share to Embryo, Mammalian
Share to Embryonic and Fetal Development

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12750314
DOI: 10.1161/01.RES.0000077045.84609.9F

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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