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Article

Genetic reversion in an acute myelogenous leukemia cell line from a Fanconi anemia patient with biallelic mutations in BRCA2.

Cancer research - 15 May 2003

Ikeda Hideyuki, Matsushita Maiko, Waisfisz Quinten, Kinoshita Akitoshi, Oostra Anneke B, Nieuwint Aggie W M, De Winter Johan P, Hoatlin Maureen E, Kawai Yohko, Sasaki Masao S, D'Andrea Alan D, Kawakami Yutaka, Joenje Hans

Abstract excerpt

A 2-year old boy was diagnosed with Fanconi anemia (FA) and acute myeloid leukemia (AML). A cell line (termed FA-AML1) was established from blast cells obtained after a second relapse after a successful bone marrow transplant. Histochemical and surface marker analysis confirmed that the cells were derived from the myeloid lineage. Cytogenetic analysis revealed multiple chromosomal aberrations, including a ring 7....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, BRCA2

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Source

Identifiers

PMID: 12750298

Genes

BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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