Article
Human IgG1/IgG3 cryoglobulin suggesting lack of allelic exclusion.
Molecular immunology - 1 Jun 2003
Mohanty Subhasis, Weiner Stefan Marcus, Mentele Reinhardt, Vaith Peter, Lottspeich Friedrich, Illges Harald
Abstract excerpt
Immunoglobulins undergoing cold-dependent precipitation are known as cryoglobulins. A type I cryoglobulin after Brouet et al. from serum of a patient with severe cutaneous vasculitis and membranoproliferative glomerulonephritis was purified by reversible temperature-dependent precipitation and analyzed using FPLC, Western blotting and peptide sequencing. The isolated cryoglobulin consisted of a single complex of...
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