Article
IgG red blood cell autoantibodies in autoimmune hemolytic anemia bind to epitopes on red blood cell membrane band 3 glycoprotein.
The Journal of laboratory and clinical medicine - 1 Jan 1990
Victoria E J, Pierce S W, Branks M J, Masouredis S P
Abstract excerpt
Red blood cell (RBC) autoantibodies from patients with IgG warm-type autoimmune hemolytic anemia were labeled with iodine 125 and their RBC binding behavior characterized. Epitope-bearing RBC membrane polypeptides were identified after autoantibody immunoprecipitation of labeled membranes and imm...
Topics
- Aged
- Anemia, Hemolytic, Autoimmune
- Anion Exchange Protein 1, Erythrocyte
- Autoantibodies
- Chymotrypsin
- Epitopes
- Erythrocytes
- Female
- Humans
- Immunoblotting
- Immunoglobulin G
- Immunohistochemistry
- Iodine Radioisotopes
- Isoelectric Focusing
- Male
- Middle Aged
- Phenotype
- Precipitin Tests