Article
A splice variant acquiring an extra transcript leader region decreases the translation of glutamine synthetase gene.
The Biochemical journal - 15 Aug 2003
Shin Daesung, Park Sangjin, Park Chankyu
Abstract excerpt
The expression of glutamine synthetase (GS), catalysing the ATP-dependent conversion of glutamate and ammonia into glutamine, is transcriptionally and post-transcriptionally regulated. The genomic structure of dog GS shown in the present study is basically similar to that of other mammals in that it is composed of seven exons and six introns. Using 5'-cRACE (where cRACE stands for circular rapid amplification of...
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