Article
Psoriatic arthritis: genetics and pathogenesis.
Reumatismo - 5 Jun 2012
Cauli A, Mathieu A
Abstract excerpt
Psoriatic arthritis is a complex disease affecting primarily peripheral and axial joints and entheses together with the skin. The pathogenesis is characterized by a genetic background and by inflammatory mechanisms which may be triggered by environmental factors. Several susceptibility genes have been investigated; they include HLA genes, genes within the HLA region and genes outside the HLA region. T cells,...
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