Article
Functional and prognostic relevance of the -173 polymorphism of the macrophage migration inhibitory factor gene in systemic-onset juvenile idiopathic arthritis.
Arthritis and rheumatism - 1 May 2003
De Benedetti Fabrizio, Meazza Cristina, Vivarelli Marina, Rossi Federica, Pistorio Angela, Lamb Rebecca, Lunt Mark, Thomson Wendy, Ravelli Angelo, Donn Rachelle, Martini Alberto
Abstract excerpt
OBJECTIVE: To address the functional and prognostic relevance of the -173 single-nucleotide G-to-C polymorphism of the macrophage migration inhibitory factor (MIF) gene in patients with systemic-onset juvenile idiopathic arthritis (systemic-onset JIA) by evaluating its association with serum and synovial fluid levels of MIF, with glucocorticoid requirement, and with the outcome of the disease. METHODS: A total of...
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