Article
Mutational analysis of the pancreatic secretory trypsin inhibitor gene in familial and juvenile pancreatitis in Japan.
Journal of gastroenterology - 1 Jan 2003
Kuwata Kinuko, Hirota Masahiko, Nishimori Isao, Otsuki Makoto, Ogawa Michio
Abstract excerpt
BACKGROUND: Mutations in the pancreatic secretory trypsin inhibitor ( PSTI) gene have been reported in patients suffering from chronic pancreatitis. The aim of the present study was to investigate whether similar gene mutations are present in familial and juvenile pancreatitis patients in Japan. METHODS: All four exons of the PSTI gene and their flanking intronic sequences were amplified by polymerase chain...
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