Article
Prospective epidemiologic study of the outcome and cost-effectiveness of antenatal screening to detect neonatal alloimmune thrombocytopenia due to anti-HPA-1a.
Transfusion - 1 Dec 2005
Turner Marc L, Bessos Hagop, Fagge Timothy, Harkness Mairi, Rentoul Frances, Seymour Janelle, Wilson David, Gray Irene, Ahya Ridheesh, Cairns John, Urbaniak Stan
Abstract excerpt
BACKGROUND: To assess the value of antenatal screening to detect neonatal alloimmune thrombocytopenia (NAIT) due to anti-HPA-1a, a prospective study was carried out to quantify the potential clinical benefits and determine whether screening would be cost-effective. STUDY DESIGN AND METHODS: An observational prospective controlled study was carried out on 26,506 pregnant women over 2 years. HPA-1a phenotyping was...
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