Article
Neonatal alloimmune thrombocytopenia caused by anti-HPA antibodies in pregnant Chinese women: a study protocol for a multicentre, prospective cohort trial.
BMC pregnancy and childbirth - 31 Aug 2017
Chen Li, Liu Zhiwei, Liu Tiemei, Ma Xianjun, Rao Meiying, Wang Yongjun, Sun Bo, Yin Wen, Zhang Jun, Yan Beizhan, Li Xiaojuan, Wang Qiushi, Zhang Lei, Wen Jun, Liu Fenghua, Wang Peng, Wei Yaming, Huang Yuanshuai, Wu Jiang, Guo Yi, Kang Yinlan, Song Xiaochuan, Liu Xiangfu, Zhang Genling, Xie Tingting, Chen Yonggeng, Zeng Xiaojing, Li Zhongjun
Abstract excerpt
BACKGROUND: Neonatal alloimmune thrombocytopenia (NAIT), caused by maternal antibodies raised against alloantigens carried on foetal platelets, is a very common haematological abnormality in newborns worldwide. However, baseline data on NAIT in China are lacking. Therefore, this study seeks to explore the incidence of alloantibody against the human platelet antigen (HPA) in pregnant women and its associations...
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