Association of single-nucleotide polymorphisms in the polymeric immunoglobulin receptor gene with immunoglobulin A nephropathy (IgAN) in Japanese patients.

doi:10.1007/s10038-003-0027-1

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Article

Association of single-nucleotide polymorphisms in the polymeric immunoglobulin receptor gene with immunoglobulin A nephropathy (IgAN) in Japanese patients.

Journal of human genetics - 1 Jan 2003

Obara Wataru, Iida Aritoshi, Suzuki Yasushi, Tanaka Toshihiro, Akiyama Fumihiro, Maeda Shiro, Ohnishi Yozo, Yamada Ryo, Tsunoda Tatsuhiko, Takei Takashi, Ito Kyoko, Honda Kazuho, Uchida Keiko, Tsuchiya Ken, Yumura Wako, Ujiie Takashi, Nagane Yutaka, Nitta Kosaku, Miyano Satoru, Narita Ichiei, Gejyo Fumitake, Nihei Hiroshi, Fujioka Tomoaki, Nakamura Yusuke

Abstract excerpt

Immunoglobulin A nephropathy (IgAN) is a primary glomerulonephritis of common incidence world-wide whose etiology and pathogenesis remain unresolved, although genetic factors are assumed to be involved in the development and progression of this disease. To identify genetic variations that might confer susceptibility to IgAN, we performed a case-control association study involving 389 Japanese IgAN patients and...

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PMID: 12740691
DOI: 10.1007/s10038-003-0027-1

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